反应详情

A mixture of 100 mg of 3-oxo-6-pyridin-4-yl-2,3-dihydro-pyridazine-4-carboxylic acid hydrazide, 130 mg thioacetamide, 87 mg triethylamine, 1 ml of pyridine and 5 ml of butanol is refluxed for 15 hours. After cooling and stirring at room temperature a solid precipitated is collected by filtration, washed with cold isopropanol and dried in vacuo.

1. temperatureis refluxed for 15 hours
2. temperatureAfter cooling
3. customprecipitated
4. filtrationis collected by filtration
5. washwashed with cold isopropanol
6. customdried in vacuo