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HRID2234232

反应详情

EQUATION

反应方程式

HRID 2234232 的结构方程式

REACTANTS

反应物

1
结构：CN(C)CCC(Oc1cccc2ccccc12)c1cccs1.O=C([O-])[C@@H](O)[C@H](O)C(=O)[O-]
HCID86625060

未命名化合物

PRODUCTS

生成物

1
结构：CN(C)CC[C@H](Oc1cccc2ccccc12)c1cccs1.O=C([O-])[C@@H](O)[C@H](O)C(=O)[O-]
HCID86625059

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1CCOC1
溶剂HCID8028

Tetrahydrofuran

C4H8O

PROCEDURE

实验过程

(RS)-N,N-dimethyl-3-(naphthyloxy)-3-(2-thienyl)propylamine-D-tartrate (461 g) is dissolved in tetrahydrofuran (900 ml) while hot. After cooling down to lab temperature, the mixture is stirred for 24 hours. The precipitated crystals are re-crystallized from tetrahydrofuran (400 ml) once more using the same procedure. The yield is 117 g (25%). Optical purity is 99% ee (CE).

WORKUP

后处理

  1. temperatureAfter cooling down to lab temperature
  2. customThe precipitated crystals are re-crystallized from tetrahydrofuran (400 ml)