Triethylamine → HCID 21920917, compound

HRID 2234802Notes

Reaction equation

HRID 2234802 reaction equation
[NH2:1][CH:2]1[CH2:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][C:8]=2[CH3:11])[CH2:3]1.C(N(CC)CC)C.[F:19][C:20]1[CH:28]=[CH:27][C:23]([C:24](Cl)=[O:25])=[CH:22][CH:21]=1>O1CCOCC1>[F:19][C:20]1[CH:28]=[CH:27][C:23]([C:24]([NH:1][CH:2]2[CH2:10][C:9]3[C:4](=[CH:5][CH:6]=[CH:7][C:8]=3[CH3:11])[CH2:3]2)=[O:25])=[CH:22][CH:21]=1

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 678794-Fluorobenzoyl chlorideHCID 123372084-Methyl-2,3-dihydro-1H-inden-2-amine

Product 1

HCID 21920917HCID 21920917, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

370 mg (2.52 mmol) 2-amino-4-methylindane and 257 mg (2.52 mmol) triethylamine were dissolved in 5 ml dioxane, 400 mg (2.52 mmol) 4-fluorobenzoylchloride were added, and the mixture was stirred for 2 h at room temperature (RT).

Sources & evidence

ORD record
ord-9c91932c5f2e45f196fcb05d1a288e99
Source dataset
uspto-grants-2010_05
Patent number
US07713963B2

Reaction notes

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