Triethylsilane → HCID 136029342, compound

HRID 2234845Notes

Reaction equation

HRID 2234845 reaction equation
[CH2:1]([C:3]1[O:4][C:5]([C:8]2[CH:13]=[CH:12][C:11]([S:14]C(C3C=CC=CC=3)(C3C=CC=CC=3)C3C=CC=CC=3)=[CH:10][CH:9]=2)=[N:6][N:7]=1)[CH3:2].C([SiH](CC)CC)C>FC(F)(F)C(O)=O>[CH2:1]([C:3]1[O:4][C:5]([C:8]2[CH:13]=[CH:12][C:11]([SH:14])=[CH:10][CH:9]=2)=[N:6][N:7]=1)[CH3:2]

Participants

4

Reactant 2

HCID 12052TriethylsilaneHCID 684883312-Ethyl-5-(4-(tritylthio)phenyl)-1,3,4-oxadiazole

Product 1

HCID 136029342HCID 136029342, compound

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

2-Ethyl-5-(4-(tritylthio)phenyl)-1,3,4-oxadiazole was dissolved in trifluoroacetic acid (5 ml) and a large excess of triethyl silane (500 μl) was added. The solution was stirred for 10 minutes then the solvent was removed under a stream of nitrogen to leave 4-(5-ethyl-1,3,4-oxadiazol-2-yl)benzenethiol-Compound F 98 mg (99%).

Workup

  1. customthe solvent was removed under a stream of nitrogen

Sources & evidence

ORD record
ord-341891d69c5442a5bc5cf4cc492010eb
Source dataset
uspto-grants-2010_05
Patent number
US07713973B2

Reaction notes

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