Itaconic acid → HCID 67525014, compound

HRID 2235047Notes

Reaction equation

HRID 2235047 reaction equation
[NH2:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([O:8][CH3:9])=[O:7])=[C:4]([CH3:12])[CH:3]=1.[C:13]([OH:21])(=[O:20])[C:14]([CH2:16][C:17](O)=[O:18])=[CH2:15]>C1(C)C(C)=CC=CC=1>[CH3:9][O:8][C:6]([C:5]1[CH:10]=[CH:11][C:2]([N:1]2[C:17](=[O:18])[CH2:16][CH:14]([C:13]([OH:21])=[O:20])[CH2:15]2)=[CH:3][C:4]=1[CH3:12])=[O:7]

Participants

4

Reactant 2

HCID 811Itaconic acidHCID 11672721Methyl 4-amino-2-methylbenzoate

Product 1

HCID 67525014HCID 67525014, compound

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

10 g (60.5 mmol) methyl 4-amino-2-methyl-benzoate and 7.9 g (60.5 mmol) itaconic acid are suspended in 50 ml xylene and refluxed for seven hours. The reaction mixture is cooled to ambient temperature and evaporated to dryness. The residue is suspended in methanol. The undissolved solid is filtered off and dried until the weight remains constant.

Workup

  1. temperaturerefluxed for seven hours
  2. customevaporated to dryness
  3. filtrationThe undissolved solid is filtered off
  4. customdried until the weight

Sources & evidence

ORD record
ord-a71f0c9cb11f4c3f817b09d653693995
Source dataset
uspto-grants-2010_05
Patent number
US07714000B2

Reaction notes

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