2-Chloro-5-nitropyridine → HCID 67536866, compound

HRID 2236162Notes

Reaction equation

HRID 2236162 reaction equation
[CH3:1][O:2][CH2:3][CH:4]([NH2:6])[CH3:5].Cl[C:8]1[CH:13]=[CH:12][C:11]([N+:14]([O-:16])=[O:15])=[CH:10][N:9]=1>>[CH3:1][O:2][CH2:3][CH:4]([N:6]1[CH:10]=[C:11]([N+:14]([O-:16])=[O:15])[CH:12]=[CH:13][CH:8]1[NH2:9])[CH3:5]

Participants

3

Reactant 2

HCID 783082-Chloro-5-nitropyridineHCID 123458Methoxyisopropylamine

Product 1

HCID 67536866HCID 67536866, compound

Procedure

This compound was prepared with the same method described before by using 2-methoxy-1-methylethylamine and 2-chloro-5-nitro-pyridine to give N-(2-methoxy-1-methylethyl)-2-amino-5-nitro-pyridine. LCMS calcd for C9H13N3O3 m/e 211.22, obsd 210.2 (AP, M−H). The nitro compound was hydrogenated under the same condition described before to give N2-(2-methoxy-1-methylethyl)-2,5-diaminopyridine.

Workup

  1. customThis compound was prepared with the same method

Sources & evidence

ORD record
ord-b9ccc7ba0cc84b75b65640107d55d964
Source dataset
uspto-grants-2010_05
Patent number
US07714126B2

Reaction notes

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