Hydrochloric Acid → HCID 73678917, compound

HRID 223644Notes

Reaction equation

HRID 223644 reaction equation
[CH2:1]([C:3]1([CH2:21][CH3:22])[CH2:14][CH:13]=[CH:12][CH2:11][CH2:10][CH:9]=[CH:8][CH2:7][CH:6]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[N:5]=[CH:4]1)[CH3:2].Cl.Cl.[NH2:25][OH:26]>O>[CH2:1]([C:3]([CH2:21][CH3:22])([CH2:14][CH:13]=[CH:12][CH2:11][CH2:10][CH:9]=[CH:8][CH2:7][CH:6]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)[NH2:5])[CH:4]=[N:25][OH:26])[CH3:2]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 443297Hydroxyamine hydrochlorideHCID 53954647HCID 53954647, compound

Product 1

HCID 73678917HCID 73678917, compoundYield 97.5%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

The procedure described in Example 1(b) is repeated, except that 95.3 g (0.323 mol) of 3,3-diethyl-12-phenyl-1-aza-1,5,9-cyclododecatriene, 20 g of 37% hydrochloric acid, 22.4 g (0.322 mol) of hydroxylamine hydrochloride and 250 ml of water are used. Working up yields 103.1 g (0.314 mol) of 2,2-diethyl-11-phenyl-11-amino-undeca-4,8-dienal oxime; yield 97.5% of theory.

Sources & evidence

ORD record
ord-734fcf09804f4bda8a1458f3abc895a8
Source dataset
uspto-grants-1982_10
Patent number
US04355177

Reaction notes

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