反应详情

温度

60 °C

A mixture of N-[4-(3-methoxyamino-propyl)-phenyl]-acetamide (0.50 mmol) and 20% aqueous hydrochloric acid (2 mL) in methanol (8 mL) is heated for 18 hours at 60° C. and then concentrated under reduced pressure to give N-[3-(4-amino-phenyl)-propyl]-O-methyl-hydroxylamine dihydrochloride (62 mg, 0.24 mmol) and is used in the following step without further purification.

1. concentrationconcentrated under reduced pressure