1-Iodopropane → 6-Bromo-4-isopropyl-2,2,7-trimethyl-4H-benzo[1,4]oxazin-3-one

HRID 2239247Notes

Reaction equation

HRID 2239247 reaction equation
[Br:1][C:2]1[C:3]([CH3:17])=[CH:4][C:5]2[O:10][C:9]([CH3:12])([CH3:11])[C:8](=[O:13])[N:7]([CH2:14][CH3:15])[C:6]=2[CH:16]=1.[CH2:18](I)CC>>[Br:1][C:2]1[C:3]([CH3:17])=[CH:4][C:5]2[O:10][C:9]([CH3:12])([CH3:11])[C:8](=[O:13])[N:7]([CH:14]([CH3:18])[CH3:15])[C:6]=2[CH:16]=1

Participants

3

Reactant 2

HCID 336431-IodopropaneHCID 685847416-Bromo-4-ethyl-2,2,7-trimethyl-4H-benzo[1,4]oxazin-3-one

Product 1

HCID 685827186-Bromo-4-isopropyl-2,2,7-trimethyl-4H-benzo[1,4]oxazin-3-one

Procedure

This was prepared using a procedure similar to that described to make Compound 1C, except using l-propyl iodide in Step C. MS (electrospray): mass calculated for C14H18BrNO2, 311.05; m/z found 312 [M+H]+.

Workup

  1. customThis was prepared

Sources & evidence

ORD record
ord-5e7611d6fd2b4fbaa3b001275912b558
Source dataset
uspto-grants-2010_05
Patent number
US07723326B2

Reaction notes

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