N-Hydroxyphthalimide → n-Hydroxyphthalimide sodium salt

HRID 2240917Notes

Reaction equation

HRID 2240917 reaction equation
[OH:1][N:2]1[C:6](=[O:7])[C:5]2=[CH:8][CH:9]=[CH:10][CH:11]=[C:4]2[C:3]1=[O:12].[Na:13]>CCO>[Na:13].[OH:1][N:2]1[C:3](=[O:12])[C:4]2=[CH:11][CH:10]=[CH:9][CH:8]=[C:5]2[C:6]1=[O:7]

Participants

4

Reactant 2

HCID 10665N-HydroxyphthalimideHCID 5360545Sodium

Product 1

HCID 67549515n-Hydroxyphthalimide sodium saltYield 98.8%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

118 g (0.723 mol) of N-hydroxyphthalimide are suspended in 700 ml of ethanol absolute. To this suspension a solution of 16.65 g (0.723 mol) of sodium in 400 ml of ethanol absolute is added dropwise under stirring. The resulting red suspension is stirred for 19 h at room temperature. The so formed red solid is sucked off, washed with 100 ml of ethanol abs. and dried in vacuo to give 133 g of a red solid.

Workup

  1. stirringThe resulting red suspension is stirred for 19 h at room temperature
  2. customThe so formed red solid
  3. washwashed with 100 ml of ethanol abs
  4. customand dried in vacuo

Sources & evidence

ORD record
ord-152d0ac51bb84d4bb690cb3fae412923
Source dataset
uspto-grants-2010_05
Patent number
US07723399B2

Reaction notes

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