Dimethylformamide dimethyl acetal → HCID 66915999, compound

HRID 2242048Notes

Reaction equation

HRID 2242048 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([N+:9]([O-:11])=[O:10])[C:4]=1[S:12]([NH2:15])(=[O:14])=[O:13].CO[CH:18](OC)[N:19]([CH3:21])[CH3:20]>CN(C=O)C>[CH3:18][N:19]([CH3:21])[CH:20]=[N:15][S:12]([C:4]1[C:3]([O:2][CH3:1])=[CH:8][CH:7]=[CH:6][C:5]=1[N+:9]([O-:11])=[O:10])(=[O:14])=[O:13]

Participants

4

Reactant 2

HCID 78373Dimethylformamide dimethyl acetalHCID 66915997Benzenesulfonamide, 2-methoxy-6-nitro-

Product 1

HCID 66915999HCID 66915999, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A solution of 2-methoxy-6-nitro-benzenesulfonamide (904 mg, 3.89 mmol) and N,N-dimethyl-formamide dimethyl-acetal (0.78 mL, 5.83 mmol) in DMF (20 mL) is heated for 30 min to 60° C. Evaporation of volatiles at 50° C. under reduced pressure, addition of MeOH to the solid residue, and filtration gives N-[1-dimethylamino-methylidene]-2-nitro-6-methoxy-benzenesulfonamide.

Workup

  1. customEvaporation of volatiles at 50° C.
  2. additionunder reduced pressure, addition of MeOH
  3. filtrationto the solid residue, and filtration

Sources & evidence

ORD record
ord-0a120100ac3b4a69aa409f1db2092ec5
Source dataset
uspto-grants-2010_03
Patent number
US07671063B2

Reaction notes

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