反应详情

tert-Butyl 4-{4-[ethyl(1-methyl-2-oxo-2-phenylethyl)carbamoyl]thiazol-2-yl}-piperidine-1-carboxylate (5.5 mmol; 2.59 g) is dissolved in 13.75 ml of a 4M solution of hydrochloric acid in dioxane. The reaction medium is stirred at room temperature overnight and is then evaporated to dryness to give 2.24 g of a white solid.

1. customis then evaporated to dryness