Water → 4-Amino-3-bromobenzoic acid

HRID 2243441Notes

Reaction equation

HRID 2243441 reaction equation
[NH2:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=1.[Br:11]N1C(=O)CCC1=O.O>CN(C=O)C>[NH2:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][C:3]=1[Br:11]

Participants

5

Reactant 3

HCID 962WaterHCID 9784-Aminobenzoic AcidHCID 67184N-bromobutanimide

Product 1

HCID 2389354-Amino-3-bromobenzoic acidYield 70%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

4-Amino-benzoic acid (100 mmol) was dissolved in DMF (50 mL) and N-bromosuccinimide (100 mmol) was added. Stirred at ambient temperature for 18 h, the reaction mixture was then poured into water (100 mL). The product was removed by filtration, washed with water and dried in vacuo to give 4-amino-3-bromo-benzoic acid.

Workup

  1. customThe product was removed by filtration
  2. washwashed with water
  3. customdried in vacuo

Sources & evidence

ORD record
ord-0bb57b91eb7849a5baba823937559782
Source dataset
uspto-grants-2010_03
Patent number
US07674912B2

Reaction notes

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