HCID 12878341, compound → HCID 12878342, compound

HRID 224433Notes

Reaction equation

HRID 224433 reaction equation
O[CH:2]([C:8]1[CH:13]=[CH:12][C:11]([CH:14]2[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]2)=[CH:10][C:9]=1[O:20][CH3:21])[CH2:3][CH2:4][C:5]([OH:7])=[O:6]>C(OCC)(=O)C.[Pd]>[CH:14]1([C:11]2[CH:12]=[CH:13][C:8]([CH2:2][CH2:3][CH2:4][C:5]([OH:7])=[O:6])=[C:9]([O:20][CH3:21])[CH:10]=2)[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19]1

Participants

4

Reactant 1

HCID 12878341HCID 12878341, compound

Product 1

HCID 12878342HCID 12878342, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

1 g of 4-hydroxy-4-(4-cyclohexyl-2-methoxyphenyl)-butyric acid is dissolved in 20 ml of ethyl acetate and hydrogenated in the presence of 100 mg of Pd on carbon (10%). When the hydrogen has been completely absorbed, filtration takes place. The filtrate is evaporated and the residue is recrystallised from CH2Cl2 -pentane. M.p. 104°-105°.

Workup

  1. customWhen the hydrogen has been completely absorbed
  2. filtrationfiltration
  3. customThe filtrate is evaporated
  4. customthe residue is recrystallised from CH2Cl2 -pentane

Sources & evidence

ORD record
ord-3d02b2c493fa4130baead1da5e04055c
Source dataset
uspto-grants-1980_11
Patent number
US04232039

Reaction notes

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