Phosgene → HCID 54247646, compound

HRID 224525Notes

Reaction equation

HRID 224525 reaction equation
[O:1]([CH:8]([C:11]1[S:15][C:14]([NH2:16])=[N:13][N:12]=1)[CH2:9][CH3:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:17](Cl)(Cl)=[O:18]>C(OC(=O)C)C>[O:1]([CH:8]([C:11]1[S:15][C:14]([N:16]=[C:17]=[O:18])=[N:13][N:12]=1)[CH2:9][CH3:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 6371PhosgeneHCID 2771921HCID 2771921, compound

Product 1

HCID 54247646HCID 54247646, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The procedure of Example Ib was followed using 8 g. of the 5-(1-phenoxypropyl)-2-amino-1,3,4-thiadiazole (prepared above) and 100 ml. of ethylacetate saturated with phosgene. Topping and removing of the phosgene resulted in a glassy, orange residue of 5-(1-phenoxypropyl)-1,3,4-thiadiazol-2-yl isocyanate dimer (10.9 grams).

Workup

  1. customTopping and removing of the phosgene

Sources & evidence

ORD record
ord-dda3619240144b5bb504e8c3301fcb05
Source dataset
uspto-grants-1980_11
Patent number
US04233057

Reaction notes

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