反应详情

40.5 g of 6-amino-3-methyl-5-nitroso-1-phenyl-2,4-(1H, 3H)-pyrimidinedione (XVII) in 500 ml of DMF and in the presence of 0.3 g of PtO2 was the solution catalytically hydrogenated for 20 minutes at a pressure of 200 kPa. The reaction mixture was heated and the catalyst was filtered off. After cooling, crystals were filtered off and washed with DMF and water. Yield 21.4 g (XVIII). NMR

1. temperatureThe reaction mixture was heated
2. filtrationthe catalyst was filtered off
3. temperatureAfter cooling
4. filtrationcrystals were filtered off
5. washwashed with DMF and water