反应详情

温度

70 °C

A mixture of Compound 3 (300 mg) and potassium thioacetate (400 mg) in N,N-dimethylformamide (2 mL) was heated at 70° C. under argon for 16 hours. The N,N-dimethylformamide was removed under vacuum and the resulting residue was directly eluted on a silica gel using 1% ethanol in dichloromethane to obtain the required product in 74% yield (240 mg).

1. customThe N,N-dimethylformamide was removed under vacuum
2. washthe resulting residue was directly eluted on a silica gel using 1% ethanol in dichloromethane