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HRID2246630

反应详情

EQUATION

反应方程式

HRID 2246630 的结构方程式

REACTANTS

反应物

3
结构：BrCC1CCCO1
HCID14501

Furan, 2-(bromomethyl)tetrahydro-

C5H9BrO

结构：[H-].[Na+]
HCID24758

Sodium hydride

HNa

结构：Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccc2[nH]ncc2c1
HCID10403067

N-Cyclopropyl-3-fluoro-5-(1H-indazol-5-yl)-4-methylbenzamide

C18H16FN3O

2 次

PRODUCTS

生成物

1
结构：Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccc2c(cnn2CC2CCCO2)c1
HCID58899620

未命名化合物

收率 29.7%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

The procedure for Example 1 was followed using sodium hydride (60% in mineral oil, 12 mg), N-cyclopropyl-3-fluoro-5-(1H-indazol-5-yl)-4-methylbenzamide (Intermediate 3, 45 mg) and 2-(bromomethyl)tetrahydrofuran (26 mg) in DMF (5 ml) to give the title compound as a colourless glass (17 mg).