2-(Dimethylamino)ethanol → HCID 23330312, compound

HRID 224765Notes

Reaction equation

HRID 224765 reaction equation
[CH3:1][N:2]([CH3:6])[CH2:3][CH2:4][OH:5].[N+:7]([C:10]1[CH:15]=[CH:14][C:13]([O:16][C:17]([Cl:19])=[O:18])=[CH:12][CH:11]=1)([O-:9])=[O:8]>C(#N)C>[ClH:19].[C:17](=[O:18])([O:5][CH2:4][CH2:3][N:2]([CH3:6])[CH3:1])[O:16][C:13]1[CH:12]=[CH:11][C:10]([N+:7]([O-:9])=[O:8])=[CH:15][CH:14]=1

Participants

4

Reactant 2

HCID 79022-(Dimethylamino)ethanolHCID 821294-Nitrophenyl chloroformate

Product 1

HCID 23330312HCID 23330312, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

270 mg of 2-dimethylaminoethanol in 5 ml of acetonitrile are stirred with 630 mg of chloroformic acid p-nitrophenyl ester at room temperature for 30 minutes, the mixture is concentrated in vacuo and the residue is stirred with 2 ml of ethyl acetate; yield: 0.4 g; IR: 1770 cm-1.

Workup

  1. concentrationthe mixture is concentrated in vacuo

Sources & evidence

ORD record
ord-a6d61409dcb9419c80f69d0aedd5f4cc
Source dataset
uspto-grants-1980_11
Patent number
US04234572

Reaction notes

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