反应详情

A solution of 8.0 g (37.9 mmol) of N-benzylidenebenzylamine N-oxide and 6.69 g (77.7 mmol) of methyl acrylate in 20 ml of toluene is heated under reflux for 12 hours. The reaction mixture is evaporated under reduced pressure to give a pale yellow oil. Flash chromatography (silica gel, 2:1 heptane:ethyl acetate) affords 8.0 g of the title compound as a pale yellow oil.

1. temperatureunder reflux for 12 hours
2. customThe reaction mixture is evaporated under reduced pressure
3. customto give a pale yellow oil