Acetone → HCID 15662548, compound

HRID 2248160Notes

Reaction equation

HRID 2248160 reaction equation
Cl[CH2:2][C:3](=[O:5])[CH3:4].[CH3:6][C:7]([CH3:18])=[CH:8][CH2:9][O:10][C:11]1[CH:16]=[CH:15][C:14]([OH:17])=[CH:13][CH:12]=1.C(=O)([O-])[O-].[K+].[K+].[I-].[K+].CC(C)=O>>[CH3:6][C:7]([CH3:18])=[CH:8][CH2:9][O:10][C:11]1[CH:12]=[CH:13][C:14]([O:17][CH2:2][C:3](=[O:5])[CH3:4])=[CH:15][CH:16]=1

Participants

6

Reactant 5

HCID 180AcetoneHCID 4875Potassium IodideHCID 6571ChloroacetoneHCID 11430Potassium CarbonateHCID 11435274HCID 11435274, compound

Product 1

HCID 15662548HCID 15662548, compound

Procedure

Chloroacetone (0.89 ml, 1.04 g, 11.2 mmol) is added to a mixture of 4-(3-methyl-2-butenoxy)phenol (2.0 g, 11.2 mmol), potassium carbonate (25 g) and potassium iodide (2.6 g) in 125 mol of anhydrous acetone. The mixture is heated under reflux for 4.5 hours and then is allowed to cool to RT to give 4-(3-methyl-2-butenoxy)phenoxyacetone.

Workup

  1. temperatureThe mixture is heated
  2. temperatureunder reflux for 4.5 hours

Sources & evidence

ORD record
ord-656ebda34227434cbe3032fad8c5a86a
Source dataset
uspto-grants-1991_08
Patent number
US05037991

Reaction notes

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