Chlorosuccinimide → Methyl 2-chloro-4-methyl-3-oxo-2,3-dihydrothiophene-2-carboxylate

HRID 2248743Notes

Reaction equation

HRID 2248743 reaction equation

[Cl:1]N1C(=O)CCC1=O.OC1SC=CC=1.[OH:15][C:16]1[C:20]([CH3:21])=[CH:19][S:18][C:17]=1[C:22]([O:24][CH3:25])=[O:23]>C(Cl)(Cl)(Cl)Cl>[Cl:1][C:17]1([C:22]([O:24][CH3:25])=[O:23])[C:16](=[O:15])[C:20]([CH3:21])=[CH:19][S:18]1

Participants

5

Reactant 3

HCID 31398Chlorosuccinimide

HCID 10909502Thiophen-2-ol

HCID 54710749Methyl 3-hydroxy-4-methylthiophene-2-carboxylate

Product 1

HCID 14642334Methyl 2-chloro-4-methyl-3-oxo-2,3-dihydrothiophene-2-carboxylate

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent

Procedure

N-Chlorosuccinimide (0.027 mol) was added to a stirred solution of the hydroxythiophen of (c) above (3 g) in 8 ml of carbon tetrachloride.

Sources & evidence

ORD record: ord-13794088a2884ec4a4c8159d16c9ab53
Source dataset: uspto-grants-1991_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05041461

Reaction notes

Loading…