反应详情

1 g (30.2 mmol) of 2-(4-methoxycarbonylphenylthio)-2-tert. butoxycarbonylcyclohexanone is dissolved, together with 0.37 g (3.3 mmol) of potassium tert. butylate, in 100 ml of methanol of reagent purity and the solutions is left to stand for 2 hours at room temperature. It is then diluted with 500 ml of ethyl acetate and the organic phase is washed with water and a saturated sodium chloride solution, dried with sodium sulphate and concentrated by evaporation. After drying in a high vacuum 11.3 g of an oily product are obtained, which is sufficiently pure to be used for further reactions.

1. waitthe solutions is left
2. washthe organic phase is washed with water
3. dry with materiala saturated sodium chloride solution, dried with sodium sulphate
4. concentrationconcentrated by evaporation
5. dry with materialAfter drying in a high vacuum 11.3 g of an oily product
6. customare obtained