Creatine → HCID 86622616, compound

HRID 2249923Notes

Reaction equation

HRID 2249923 reaction equation
[O:1]=[C:2]([CH2:4][N:5]([C:7](=[NH:9])[NH2:8])[CH3:6])[OH:3].[OH-].[NH4+:11]>O>[CH3:6][N:5]([CH2:4][C:2]([O-:3])=[O:1])[C:7]([NH2:9])=[NH:8].[NH4+:11]

Participants

4

Reactant 2

HCID 586CreatineHCID 14923Ammonium Hydroxide

Product 1

HCID 86622616HCID 86622616, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Separately, in a single-necked, round bottomed flask, equipped with a magnetic stirrer, 7.87 g (60 mmol) of creatine is dissolved in 600 ml of water. To this is added 78 ml of 1M ammonium hydroxide with vigorous stirring, until heat production ceases. At this point the water is removed by evaporation to yield the carboxylate salt, ammonium 2-(1-methylguanidino)acetate, shown below.

Workup

  1. customSeparately, in a single-necked, round bottomed flask, equipped with a magnetic stirrer
  2. temperatureuntil heat production ceases
  3. customAt this point the water is removed by evaporation

Sources & evidence

ORD record
ord-02552a681a014136bc6ce0177df967f4
Source dataset
uspto-grants-2008_01
Patent number
US07314945B1

Reaction notes

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