反应详情

A mixture of 95 g of benzaldehyde, 114.3 g of 7A, 1 g of piperidine and 200 ml of acetic acid was heated on a steam bath for 1 hour. The acetic acid and unreacted benzaldehyde were distilled off, to 100° C./0.2 Torr. The residue was extracted with hot hexane; no residue was left. The solution was chilled, and the solid that formed was recrystallized from methanol to give the 1-methylethyl ester of 2-cyano-3-phenyl-2-propenoic acid (7B), mp: 72°-73° C.

1. temperaturewas heated on a steam bath for 1 hour
2. distillationThe acetic acid and unreacted benzaldehyde were distilled off, to 100° C./0.2 Torr
3. extractionThe residue was extracted with hot hexane
4. waitno residue was left
5. temperatureThe solution was chilled
6. customthe solid that formed
7. customwas recrystallized from methanol