Oxalyl chloride → HCID 53635111, compound

HRID 2251923Notes

Reaction equation

HRID 2251923 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]=[CH:8][C:9]([OH:11])=O)[CH:2]=1.C(Cl)(=O)C(Cl)=O.Cl.Cl.[S:20]([NH:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][NH2:37])([C:23]1[CH:29]=[CH:28][C:26]([CH3:27])=[CH:25][CH:24]=1)(=[O:22])=[O:21]>>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]=[CH:8][C:9]([NH:37][CH2:36][CH2:35][CH2:34][CH2:33][CH2:32][CH2:31][NH:30][S:20]([C:23]2[CH:29]=[CH:28][C:26]([CH3:27])=[CH:25][CH:24]=2)(=[O:22])=[O:21])=[O:11])[CH:2]=1

Participants

4

Reactant 3

HCID 65578Oxalyl chlorideHCID 1019843-(3-Pyridinyl)-2-propenoic acidHCID 17940753HCID 17940753, compound

Product 1

HCID 53635111HCID 53635111, compound

Procedure

Batch size: 4.1 g (27.5 mmol) 3-(3-pyridyl)-acrylic acid, 4.7 g (37.0 mmol) oxalyl chloride, 5.0 g (49.4 mmol) TEA and 8.6 g (25.0 mmol) 6-(tosylamino)-hexylamine.dihydrochloride.

Sources & evidence

ORD record
ord-4db86aa3cff14b16b7ee64f4015e276f
Source dataset
uspto-grants-2008_01
Patent number
US07320993B1

Reaction notes

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