反应详情

Example 58 was prepared using the same procedure as described for example 20, starting from N-BOC-(R)-2-(3-chloro-4-hydroxybenzyl)morpholine, example 7, intermediate (a), and 1-iodopropane. The resulting intermediate was deprotected with TFA as described for example 20 to yield the desired morpholine example 58 as a colorless oil (16 mg) after purification by HPLC.

1. customExample 58 was prepared