Sodium Bicarbonate → HCID 23329759, compound

HRID 225315Notes

Reaction equation

HRID 225315 reaction equation
Cl.[NH2:2][CH:3]([C:7]1[CH:12]=[CH:11][C:10]([OH:13])=[C:9]([CH2:14]Cl)[CH:8]=1)[C:4]([OH:6])=[O:5].C(=O)(O)[O-:17].[Na+]>O>[NH2:2][CH:3]([C:7]1[CH:12]=[CH:11][C:10]([OH:13])=[C:9]([CH2:14][OH:17])[CH:8]=1)[C:4]([OH:6])=[O:5]

Participants

4

Reactant 2

HCID 516892Sodium BicarbonateHCID 70578051(-)-alpha-Amino-3-(chloromethyl)-4-hydroxybenzeneacetic acid hydrochloride

Product 1

HCID 23329759HCID 23329759, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To a solution of (-)-α-amino-3-(chloromethyl)-4-hydroxybenzeneacetic acid hydrochloride in water is added saturated aqueous sodium bicarbonate until a pH of 7 is reached. The solution is stirred overnight and is then lyophilized to give a quantitative yield of the title compound, combined with 2 equivalents of sodium chloride.

Sources & evidence

ORD record
ord-8e308c7fbb1a4de08831010b2d9a69ec
Source dataset
uspto-grants-1980_11
Patent number
US04236002

Reaction notes

Loading…