Methyl Acrylate → HCID 86588344, compound

HRID 2253442Notes

Reaction equation

HRID 2253442 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[CH2:11][CH2:10][CH:9]=2)=[CH:4][CH:3]=1.[C:18]([O:22][CH3:23])(=[O:21])[CH:19]=[CH2:20]>CC#N>[CH3:23][O:22][C:18](=[O:21])[CH:19]=[CH:20][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[CH2:11][CH2:10][CH:9]=2)=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 7294Methyl AcrylateHCID 12332256HCID 12332256, compound

Product 1

HCID 86588344HCID 86588344, compoundYield 74%

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

Prepared from the Heck coupling of 4-(4-bromophenyl)-1,2-dihydro-naphthalene (2i, compound I, R3=H, X=Br, and n=1) and methyl acrylate in accordance with the general method described in Example IV (J. Chem. Soc. B, 1969, 638-643). Yield 74%; APcI m/z: 332 (M+H+CH3CN+, 100%).

Sources & evidence

ORD record
ord-a90cc08d5c2948bb82610e7c72e146ab
Source dataset
uspto-grants-2008_01
Patent number
US07323587B2

Reaction notes

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