反应详情

After dissolving 1.0 g of N-ethyl-homoveratrylamine in a solvent mixture consisting of 6 ml of a 48% aqueous hydrogen bromide solution and 4 ml of acetic acid, the solution was heated at 120°-130° C. with stirring for 5 hours. The solvent was distilled off and the residue was crystallized from ether to obtain 1.2 g of crude crystals. N-Ethyl-3,4-dihydroxyphenethylamine hydrobromide having a melting point of 149°-151° C. was obtained by recrystallizing from isopropyl alcohol. The yield was 0.68 g.

1. temperaturethe solution was heated at 120°-130° C.
2. distillationThe solvent was distilled off
3. customthe residue was crystallized from ether
4. customto obtain 1.2 g of crude crystals