HCID 4674816, compound → HCID 53710459, compound

HRID 2254454Notes

Reaction equation

HRID 2254454 reaction equation
[S:1]1[CH:5]=[CH:4][C:3]([C:6]2[S:10][C:9]([CH:11]=[O:12])=[CH:8][CH:7]=2)=[CH:2]1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>O1CCCC1>[S:1]1[CH:5]=[CH:4][C:3]([C:6]2[S:10][C:9]([CH2:11][OH:12])=[CH:8][CH:7]=2)=[CH:2]1

Participants

4

Reactant 2

HCID 4674816HCID 4674816, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 53710459HCID 53710459, compoundYield 92.1%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

144 mg of the resulting aldehyde compound was reduced with 15.6 mg of lithium aluminium hydride in 4 ml of tetrahydrofuran, and then worked up in a customary manner to give 134 mg (yield 92%) of the captioned compound as a colorless oil.

Sources & evidence

ORD record
ord-9c4b7abe3b1c458ca78c82ad890147e5
Source dataset
uspto-grants-1993_08
Patent number
US05234946

Reaction notes

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