Potassium Carbonate → HCID 921388, compound

HRID 2254673Notes

Reaction equation

HRID 2254673 reaction equation
[CH3:1][NH:2][CH:3](O)[CH3:4].C(=O)([O-])[O-:7].[K+].[K+].[C:12]1([CH:18]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[C:19](Cl)=[O:20])[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>CC(C)=O>[OH:7][CH2:4][CH2:3][N:2]([CH3:1])[C:19](=[O:20])[CH:18]([C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 746372,2-Diphenylacetyl chlorideHCID 5247031N-Methylaminoethanol

Product 1

HCID 921388HCID 921388, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

To a mixture of 9 g (0.12 mole) of N-methylaminoethanol and 17 g (0.12 mole) of potassium carbonate in 100 ml of acetone was added 25 g (0.11 mole) 2,2-diphenylacetylchloride. The mixture was stirred for 0.5 hours and then refluxed for 3 hours. The mixture was cooled and filtered. The salt was extracted with 3×125 ml methylene chloride. The collected organic extracts were evaporated.

Workup

  1. temperaturerefluxed for 3 hours
  2. temperatureThe mixture was cooled
  3. filtrationfiltered
  4. extractionThe salt was extracted with 3×125 ml methylene chloride
  5. customThe collected organic extracts were evaporated

Sources & evidence

ORD record
ord-e9ce55fb60d941f9ae0c413af304b918
Source dataset
uspto-grants-1993_08
Patent number
US05236956

Reaction notes

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