4-Hydroxybenzaldehyde → HCID 178444467, compound

HRID 2254995Notes

Reaction equation

HRID 2254995 reaction equation
[OH:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[O:7])=[CH:4][CH:3]=1.[CH2:10]([C@H:15]1[CH2:20][CH2:19][C@H:18]([CH2:21][CH2:22][CH2:23]Br)[CH2:17][CH2:16]1)[CH2:11][CH2:12][CH2:13][CH3:14].C(=O)([O-])[O-].[K+].[K+]>CC(=O)CC>[CH2:10]([C@H:15]1[CH2:20][CH2:19][C@H:18]([CH2:21][CH2:22][CH2:23][O:1][C:2]2[CH:9]=[CH:8][C:5]([CH:6]=[O:7])=[CH:4][CH:3]=2)[CH2:17][CH2:16]1)[CH2:11][CH2:12][CH2:13][CH3:14]

Participants

5

Reactant 3

HCID 1264-HydroxybenzaldehydeHCID 11430Potassium CarbonateHCID 178444432HCID 178444432, compound

Product 1

HCID 178444467HCID 178444467, compoundYield 121.9%

Reagents, catalysts & solvents 1

HCID 6569Methyl Ethyl KetoneSolvent

Procedure

1.9 g of 4-hydroxybenzaldehyde, 5.0 g of 3-(trans-4-pentylcyclohexyl)-1-propyl bromide 8.3 g of potassium carbonate and 50 ml of butanone were reacted in an analogous manner to Example 1 to give 6.0 g of 4-[3-(trans-4-pentylcyclohexyl)-1-propyloxy]benzaldehyde.

Sources & evidence

ORD record
ord-561c651255ea48d7b4e56db6d960125f
Source dataset
uspto-grants-1993_08
Patent number
US05238600

Reaction notes

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