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HRID2255608

反应详情

EQUATION

反应方程式

HRID 2255608 的结构方程式

REACTANTS

反应物

4
结构：OCc1ccc(O)cc1
HCID125

4-Hydroxybenzenemethanol

C7H8O2

结构：Oc1ccccc1
HCID996

Phenol

C6H6O

结构：COC(=O)CBr
HCID60984

Methyl bromoacetate

C3H5BrO2

结构：CC(C)=O.O=C([O-])[O-].[K+].[K+]
HCID86600397

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)COc1ccc(CO)cc1
HCID690034

Acetic acid, [4-(hydroxymethyl)phenoxy]-, methyl ester

C10H12O4

收率 48%

PROCEDURE

实验过程

Using the K2CO3 /acetone conditions for phenol alkylation described in Step A of Example 30, 8.00 g (64.5 mmol) of 4-hydroxybenzyl alcohol was alkylated with 11.84 g (77.4 mmol) of methyl bromoacetate to afford 6.00 g (48%) of the title compound.