Hydrochloric Acid → HCID 19027820, compound

HRID 2257187Notes

Reaction equation

HRID 2257187 reaction equation
[N+:1]([C:4]1[C:13]([S:14][CH3:15])=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[N:7][N:8]=[CH:9]2)([O-])=O.[Sn](Cl)Cl.Cl>>[NH2:1][C:4]1[C:13]([S:14][CH3:15])=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[N:7][N:8]=[CH:9]2

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 24479Stannous ChlorideHCID 19027884HCID 19027884, compound

Product 1

HCID 19027820HCID 19027820, compound

Procedure

5-Nitro-6-methylthiophthalazine, prepared as described by Sturrock et al., Can. J, Chem., 49, 3047 (1971) and Hirsch & Orphanos, J. Heterocyclic Chem., 2, 206 (1965), was reduced with tin (II ) chloride and HCl to yield 5-amino-6-methylthiophthalazine. This material was coupled with commercially available oleoyl chloride to yield the title compound.

Sources & evidence

ORD record
ord-40b44d0c557a4fbe9a1a18b387cc4041
Source dataset
uspto-grants-1997_08
Patent number
US05656634

Reaction notes

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