6-Methoxy-2-(1-cyclohexenyl)benzo[b]thiophene → 6-Methoxy-2-cyclohexylbenzo[b]thiophene

HRID 2259209Notes

Reaction equation

HRID 2259209 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[CH:10]=[C:9]([C:11]3[CH2:16][CH2:15][CH2:14][CH2:13][CH:12]=3)[S:8][C:7]=2[CH:17]=1>C(OCC)(=O)C.[C].[Pd]>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[CH:10]=[C:9]([CH:11]3[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]3)[S:8][C:7]=2[CH:17]=1

Participants

4

Reactant 1

HCID 235129036-Methoxy-2-(1-cyclohexenyl)benzo[b]thiophene

Product 1

HCID 108794206-Methoxy-2-cyclohexylbenzo[b]thiopheneYield 49.6%

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 8857Ethyl AcetateSolvent

Procedure

5 g of 6-methoxy-2-(1-cyclohexenyl)benzo[b]thiophene was dissolved in 20 ml of ethyl acetate, 800 mg of 5% palladium-carbon was added, and hydrogenation was carried out at room temperature and at atmospheric pressure. The reaction mixture was filtered, and the filtrate was concentrated to obtain 2.5 g of 6-methoxy-2-cyclohexylbenzo[b]thiophene.

Workup

  1. customwas carried out at room temperature and at atmospheric pressure
  2. filtrationThe reaction mixture was filtered
  3. concentrationthe filtrate was concentrated

Sources & evidence

ORD record
ord-5e1e3040b23446efa25e8ed91ab7e706
Source dataset
uspto-grants-1995_12
Patent number
US05472962

Reaction notes

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