Hydrochloric Acid → HCID 12647858, compound

HRID 2262830Notes

Reaction equation

HRID 2262830 reaction equation
C([O:5][C:6](=[O:20])[CH2:7][C:8]1([C:17]([OH:19])=[O:18])[CH2:16][C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH2:9]1)(C)(C)C.Cl>CCOC(C)=O>[C:6]([CH2:7][C:8]1([C:17]([OH:19])=[O:18])[CH2:16][C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH2:9]1)([OH:20])=[O:5]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 15298916HCID 15298916, compound

Product 1

HCID 12647858HCID 12647858, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

A solution of 2-(2-tert-butoxy-2-oxoethyl)indane-2-carboxylic acid from Step B (1.50 g, 5.43 mmol) in EtOAc (100 mL) was saturated with HCl (g) and stood at ambient temperature for 1b, then concentrated to dryness in vacuo, to give the title compound. MS: m/z=284 (M+Na+CH3CN).

Workup

  1. concentrationconcentrated to dryness in vacuo

Sources & evidence

ORD record
ord-0381524495c54e84b1acac463efe1954
Source dataset
uspto-grants-2010_12
Patent number
US07851464B2

Reaction notes

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