1-Iodopropane → HCID 68778013, compound

HRID 2263507Notes

Reaction equation

HRID 2263507 reaction equation
[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[C:9]1[CH:14]=[CH:13][N:12]=[CH:11][CH:10]=1.I[CH2:16][CH2:17][CH3:18].[BH4-].[Na+]>C(O)C>[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[C:9]1[CH2:10][CH2:11][N:12]([CH2:16][CH2:17][CH3:18])[CH2:13][CH:14]=1

Participants

5

Reactant 3

HCID 336431-IodopropaneHCID 4311764Sodium borohydrideHCID 17898951HCID 17898951, compound

Product 1

HCID 68778013HCID 68778013, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Preparation according to preparation 10: 4-(2,3-dichlorophenyl)pyridine (1.0 g, 4.46 mmol), 1-iodopropane (6 ml), ethanol (60 ml), sodium borohydride (1.5 g, 44 mmol). Yield: 0.45 g. MS m/z (rel. intensity, 70 eV) 271 (M+, 16), 269 (M+, 28), 242 (62), 240 (bp), 127 (11).

Workup

  1. customPreparation
  2. customaccording to preparation 10

Sources & evidence

ORD record
ord-689f230ce240418d9b5ea1a7b756464a
Source dataset
uspto-grants-2010_12
Patent number
US07851629B2

Reaction notes

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