HCID 57438798, compound → HCID 57438799, compound

HRID 2263508Notes

Reaction equation

HRID 2263508 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][C:11]([C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([Cl:21])[C:16]=2[Cl:22])(O)[CH2:10][CH2:9]1)=O)(C)(C)C>FC(F)(F)C(O)=O>[Cl:22][C:16]1[C:17]([Cl:21])=[CH:18][CH:19]=[CH:20][C:15]=1[C:11]1[CH2:12][CH2:13][NH:8][CH2:9][CH:10]=1

Participants

3

Reactant 1

HCID 57438798HCID 57438798, compound

Product 1

HCID 57438799HCID 57438799, compound

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

According to Preparation 4: Tert-butyl-4-(2,3-dichlorophenyl)-4-hydroxypiperidine-1-carboxylate (3.0 g, 8.7 mmol), trifluoroacetic acid (30 ml). Yield: 0.88 g. MS m/z (rel. intensity, 70 eV) 229 (63), 228 (M+, 36), 227 (bp), 163 (53), 82 (85).

Workup

  1. customAccording to Preparation 4

Sources & evidence

ORD record
ord-49a13a162cb24e56aeea842a327b3351
Source dataset
uspto-grants-2010_12
Patent number
US07851629B2

Reaction notes

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