6-Chloro-3-nitropyridin-2-ylamine → 3'-Chloro-5-nitro-2,4'-bipyridin-6-amine

HRID 2264184Notes

Reaction equation

HRID 2264184 reaction equation
CC1(C)C(C)(C)OB([C:9]2[CH:14]=[CH:13][N:12]=[CH:11][C:10]=2[Cl:15])O1.Cl[C:18]1[N:23]=[C:22]([NH2:24])[C:21]([N+:25]([O-:27])=[O:26])=[CH:20][CH:19]=1>>[Cl:15][C:10]1[CH:11]=[N:12][CH:13]=[CH:14][C:9]=1[C:18]1[CH:19]=[CH:20][C:21]([N+:25]([O-:27])=[O:26])=[C:22]([NH2:24])[N:23]=1

Participants

3

Reactant 2

HCID 27240356-Chloro-3-nitropyridin-2-ylamineHCID 447551543-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

Product 1

HCID 595960173'-Chloro-5-nitro-2,4'-bipyridin-6-amineYield 99%

Procedure

Following the same procedure as in Intermediate 1 (step a), but using 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-chloropyridine, 6-chloro-3-nitropyridin-2-amine was transformed into the title compound as a white solid (2.14 g, 99%).

Sources & evidence

ORD record
ord-6b4fce7954d64b9b8209d045f16683d0
Source dataset
uspto-grants-2010_12
Patent number
US07855202B2

Reaction notes

Loading…