Hydrochloric Acid → HCID 68428068, compound

HRID 2267161Notes

Reaction equation

HRID 2267161 reaction equation
Cl.C[C:3]1[N:7]([C:8]2[CH:9]=[N:10][CH:11]=[CH:12][CH:13]=2)[N:6]=[N:5][C:4]=1[C:14]1[CH2:15][CH2:16][N:17](C(OC(C)(C)C)=O)[CH2:18][CH:19]=1>O1CCOCC1>[N:10]1[CH:11]=[CH:12][CH:13]=[C:8]([N:7]2[CH:3]=[C:4]([C:14]3[CH2:15][CH2:16][NH:17][CH2:18][CH:19]=3)[N:5]=[N:6]2)[CH:9]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 58945819HCID 58945819, compound

Product 1

HCID 68428068HCID 68428068, compoundYield 60.1%

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

A 4N solution of hydrochloric acid in dioxane (3 ml) was added to 15 mg of tert-butyl 4-[5-methyl-1-(pyridine-3-yl)-1H-[1,2,3]triazol-4-yl]-1,2,3,6-tetrahydropyridine-1-carboxylate, the mixture was stirred at room temperature for 3 hours and the solvent was evaporated in vacuo to give 6 mg of the title compound as a white solid.

Workup

  1. customthe solvent was evaporated in vacuo

Sources & evidence

ORD record
ord-a488d47c01204ead84a4590a9dc731c2
Source dataset
uspto-grants-2010_12
Patent number
US07858800B2

Reaction notes

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