反应详情

The trans-ester 18 (104 g, 359 mmol) is hydrogenated in methanol (1700 ml) with Pd/C in the presence of one equivalent of HCl (431 ml, 359 mmol, 1.25M in MeOH). The mixture is filtered and evaporated. The residue is redissolved in ether and extracted with 1N—NaOH and brine. Evaporation gives a colourless oil.

1. filtrationThe mixture is filtered
2. customevaporated
3. dissolutionThe residue is redissolved in ether
4. extractionextracted with 1N—NaOH and brine
5. customEvaporation
6. customgives a colourless oil