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A solution of piperidine 51 (35.99 g, 130.7 mmol) in methanol is hydrogenated with Pd/C in the presence of one equivalent of HCl (104.5 ml, 130.7 mmol, 1.25M in MeOH). After filtration and evaporation, the crude is taken up in ether and washed with 1N—NaOH and brine. Drying, evaporation and distillation (0.08 mbar, 75-90 C) gave a colourless oil. Yield: 17.98 g (74%).

1. filtrationAfter filtration and evaporation
2. washwashed with 1N—NaOH and brine
3. customDrying
4. customevaporation and distillation (0.08 mbar, 75-90 C)
5. customgave a colourless oil