反应详情

6-Amino-9-benzyl-8-methoxy-2-(2-methoxyethoxy)purine (21 mg, 0.064 mmol) in concentrated hydrochloric acid (20 ml) was stirred at room temperature for 5 hours. The reaction mixture was evaporated in vacuo to dryness and 28% aqueous ammonia was added to the residue. The resulting crystals were filtered and washed with water to give the subject compound (17 mg, yield 84%).

1. customThe reaction mixture was evaporated in vacuo to dryness and 28% aqueous ammonia
2. additionwas added to the residue
3. filtrationThe resulting crystals were filtered
4. washwashed with water