Trifluoroacetic acid → HCID 86757667, compound

HRID 2269500Notes

Reaction equation

HRID 2269500 reaction equation
C([O:5][C:6]1[C:7](=[O:37])[C:8](=[O:36])[C:9]=1[NH:10][C:11]1[CH:16]=[CH:15][CH:14]=[C:13]([CH:17]([C:28]2[CH:33]=[CH:32][C:31]([O:34][CH3:35])=[CH:30][CH:29]=2)[NH:18][C:19]([CH3:27])([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[CH3:20])[CH:12]=1)(C)(C)C.FC(F)(F)C(O)=O>ClCCl>[OH:36][C:8]1[C:7](=[O:37])[C:6](=[O:5])[C:9]=1[NH:10][C:11]1[CH:16]=[CH:15][CH:14]=[C:13]([CH:17]([C:28]2[CH:29]=[CH:30][C:31]([O:34][CH3:35])=[CH:32][CH:33]=2)[NH:18][C:19]([CH3:27])([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[CH3:20])[CH:12]=1

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 86757668HCID 86757668, compound

Product 1

HCID 86757667HCID 86757667, compoundYield 99.8%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Following a similar procedure to that described in Example (55b), 1.40 g of 3-t-butoxy-4-{3-[(4-methoxyphenyl )-(1-methyl-1-phenylethylamino)methyl]phenylamino}-3-cyclobutene-1,2-dione [prepared as described in step (c) above], 10 ml of trifluoroacetic acid and 35 ml of dichloromethane were reacted, to obtain 1.24 g of the title compound as a white solid.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-7fc7f7429e4945f59d89e19d1aa60686
Source dataset
uspto-grants-2001_12
Patent number
US06329405B1

Reaction notes

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