反应详情

4-Benzyl-N,N-dimethyl-3,4-dihydro-3-oxo-2-quinoxalinecarboxamide (1.47 g) was added and dissolved in ice-cooled trifluoroacetic acid (45 ml), to which was further added triethyl silane (4.6 ml). The reaction mixture was stirred at room temperature for 3 hours, then concentrated. The residue was dissolved in ethyl acetate and washed with 10% aqueous potassium carbonate solution, water and a saturated aqueous sodium chloride solution, then dried and concentrated. The obtained crystals were washed with IPE to obtain the entitled compound (1.33 g).

1. dissolutiondissolved in ice-
2. concentrationconcentrated
3. dissolutionThe residue was dissolved in ethyl acetate
4. washwashed with 10% aqueous potassium carbonate solution, water
5. dry with materiala saturated aqueous sodium chloride solution, then dried
6. concentrationconcentrated
7. washThe obtained crystals were washed with IPE