反应详情

Experimental conditions analogous to those described for Example 141, from 103 mg (0.23 mmol) of 1-(6-bromo-pyridin-2-ylmethyl)-3-(6-chloro-pyridine-3-carbonyl)-1H-quinolin-4-one and 0.5 mL pyrrolidine in 2 mL THF. Yield: 50 mg of a yellow powder. LC-MSD, m/z for C25H21BrN4O2 [M+H]+=489.0, 491.0; HPLC retention time: 1.1 min.