Thiourea → HCID 18330802, compound

HRID 2271232Notes

Reaction equation

HRID 2271232 reaction equation
[C:1]([O:9][CH:10]([C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)[C:11]([C:13]1[CH:18]=[CH:17][C:16]([N:19]([CH3:21])[CH3:20])=[CH:15][CH:14]=1)=O)(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:28]C(N)=S>CN(C)C=O>[C:2]1([C:1]2[O:9][C:10]([C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)=[C:11]([C:13]3[CH:18]=[CH:17][C:16]([N:19]([CH3:21])[CH3:20])=[CH:15][CH:14]=3)[N:28]=2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 2723790ThioureaHCID 18330803HCID 18330803, compound

Product 1

HCID 18330802HCID 18330802, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Conditions

Temperature
160 °C

Procedure

0.5 g of 2-[4-(dimethylamino)phenyl]-2-oxo-1-phenylethyl benzoate is dissolved in 10 ml of dimethylformamide in a reactor. 0.212 g of thiourea (2 eq.) is subsequently added and the reaction mixture is left to react at reflux (160° C.) for 6 hours.

Workup

  1. waitthe reaction mixture is left
  2. customto react

Sources & evidence

ORD record
ord-2e53d88ea1514e22888599550d2e00b5
Source dataset
uspto-grants-2001_12
Patent number
US06333414B1

Reaction notes

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