Thiourea → HCID 18330796, compound

HRID 2271236Notes

Reaction equation

HRID 2271236 reaction equation
[C:1]([O:9][CH:10]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)[C:11](=O)[C:12]([CH3:15])([CH3:14])[CH3:13])(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:23]C(N)=S>CN(C)C=O>[C:2]1([C:1]2[O:9][C:10]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)=[C:11]([C:12]([CH3:15])([CH3:14])[CH3:13])[N:23]=2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 2723790ThioureaHCID 70216051HCID 70216051, compound

Product 1

HCID 18330796HCID 18330796, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Conditions

Temperature
160 °C

Procedure

0.15 g of 3,3-dimethyl-2-oxo-1-phenylbutyl benzoate is dissolved in 8 ml of dimethylformamide in a reactor. 0.2 g of thiourea (5 eq.) is subsequently added and the reaction mixture is left to react at reflux (160° C.) for 15 hours.

Workup

  1. waitthe reaction mixture is left
  2. customto react

Sources & evidence

ORD record
ord-74e74c17e3e14f12aa087305aca1ab60
Source dataset
uspto-grants-2001_12
Patent number
US06333414B1

Reaction notes

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