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HRID2273131

反应详情

EQUATION

反应方程式

HRID 2273131 的结构方程式

REACTANTS

反应物

2
反应SMILES：COC(=O)c1ccc(C2(NC(=O)[C@H]3CCCCN3Cc3cccc(C(F)(F)F)c3)CC2)cc1
HCID71204705

未命名化合物

反应SMILES：O.[Li]O
HCID178418351

未命名化合物

PRODUCTS

产物

1
反应SMILES：O=C([O-])c1ccc(C2(NC(=O)[C@H]3CCCCN3Cc3cccc(C(F)(F)F)c3)CC2)cc1.[Li+]
HCID71486666

未命名化合物

PROCEDURE

实验过程

The title compound (E9) (51 mg) was prepared according to the general procedure for esters hydrolysis starting from (R)-methyl 4-(1-(1-(3-(trifluoromethyl)benzyl)piperidine-2-carboxamido)cyclopropyl)benzoate (D26) (76 mg). (LiOH H2O: 3 eq; reaction time: 3 hrs)